Can elderly patients with colorectal cancer tolerate planned surgical treatment? A practical approach to a common dilemma

Colorectal Dis. 2009 Sep;11(7):750-5. doi: 10.1111/j.1463-1318.2008.01676.x.

Abstract

Aim: Analysing the effectiveness of a surgical procedure is mandatory in every modern health-care system. The aging of the population stresses the need for a good standard of care. This study tests the hypothesis that porthsmouth-physiologic operative severity score for enumeration of morbidity and mortality (P-POSSUM) and colorectal-POSSUM (CR-POSSUM) would be useful clinical auditing tools in colorectal cancer surgery for aged patients.

Method: One hundred and seventy-seven consecutive patients over 70 years of age underwent emergency or elective surgery from January 2003 to December 2005. Demographic, clinical and surgical information, score systems' prediction, complications and 30-day mortality data were prospectively entered in a comprehensive database. The observed over expected morbidity and mortality rate was calculated.

Results: Thirty-day observed mortality was 10.3% (19/177) while P-POSSUM and CR-POSSUM expected mortality were, respectively, 11.21% (P = NS) and 13.08% (P = NS). Overall observed morbidity was 42.7%, P-POSSUM prediction was 59.3% (P = 0.002). Morbidity and mortality data were analysed for specific subgroups of patients (resection and anastomosis/resection and stoma/palliative; emergency/elective).

Conclusion: P-POSSUM and CR-POSSUM are useful tools to predict mortality in elderly patients. P-POSSUM significantly overestimated the risk of complications. A more accurate tool for preoperative assessment for aged patients is probably needed to predict the post-surgical outcome.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Colectomy / adverse effects
  • Colectomy / mortality*
  • Colonic Neoplasms / surgery*
  • Colostomy / adverse effects
  • Colostomy / mortality*
  • Humans
  • Italy / epidemiology
  • Patient Selection
  • Predictive Value of Tests
  • Rectal Neoplasms / surgery*
  • Retrospective Studies
  • Severity of Illness Index*