Abstract
We used 909 strains to compare the population structures of the Mycobacterium tuberculosis Beijing family between different birth-year cohorts in Japan. The results revealed that the spread of a modern sublineage that has high transmissibility is currently increasing, while the spread of an ancient sublineage, STK, has significantly decreased in younger generations.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Aged
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Aged, 80 and over
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Bacterial Typing Techniques
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Female
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Genotype
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Humans
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Japan / epidemiology
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Male
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Middle Aged
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Molecular Epidemiology
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Mycobacterium tuberculosis / classification*
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Mycobacterium tuberculosis / genetics
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Mycobacterium tuberculosis / isolation & purification*
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Tuberculosis / epidemiology*
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Tuberculosis / microbiology*
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Tuberculosis / transmission