Abstract
The effect of topical dapiprazole, an alpha-adrenergic receptor blocker, in reversing mydriasis was studied in 50 subjects who received tropicamide 1% and phenylephrine 2.5%. There was a significant difference in the decrease in pupil size between the eye that received dapiprazole and the control eye. This study suggests that dapiprazole 0.5% eye drops are effective and safe in reversing mydriasis after instillation of tropicamide 1% and phenylephrine 2.5%.
Publication types
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Clinical Trial
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Randomized Controlled Trial
MeSH terms
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Adolescent
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Adrenergic alpha-Antagonists / pharmacology*
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Adult
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Aged
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Blood Pressure / drug effects
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Female
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Heart Rate / drug effects
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Humans
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Intraocular Pressure / drug effects
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Male
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Middle Aged
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Phenylephrine / antagonists & inhibitors*
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Piperazines
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Pupil / drug effects*
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Pyridines / antagonists & inhibitors*
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Triazoles / pharmacology*
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Tropicamide / antagonists & inhibitors*
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Visual Acuity / drug effects
Substances
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Adrenergic alpha-Antagonists
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Piperazines
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Pyridines
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Triazoles
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Phenylephrine
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dapiprazole
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Tropicamide