Leiyemudanosides A-C, three new bidesmosidic triterpenoid saponins from the roots of Caulophyllum robustum

Fitoterapia. 2010 Apr;81(3):200-4. doi: 10.1016/j.fitote.2009.08.025. Epub 2009 Aug 29.

Abstract

Three new oleanane bidesmosidic triterpenoid saponins, named leiyemudanosides A-C (1-3) were isolated from the roots of Caulophyllum robustum Maxim. Their structures were established by chemical and detailed spectroscopic analysis as 3-O-alpha-L-arabinopyranosyl-caulophyllogenin-28-O-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranosyl ester (1), 3-O-beta-D-glucopyranosyl-(1-->3)-alpha-L-arabinopyranosyl-caulophyllogenin-28-O-alpha-L-rhamnopyranosyl-(1-->4)-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranosyl ester (2), and 3-O-beta-D-glucopyranosyl-(1-->3)-alpha-L-arabinopyranosyl-echinocystic acid-28-O-alpha-L-rhamnopyranosyl-(1-->4)-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranosyl ester (3), respectively.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Caulophyllum / chemistry*
  • Molecular Structure
  • Plant Extracts / chemistry*
  • Plant Roots
  • Saponins / chemistry
  • Saponins / isolation & purification*

Substances

  • 3-O-arabinopyranosylcaulophyllogenin-28-O-glucopyranosyl-(1-6)-glucopyranosyl ester
  • 3-O-glucopyranosyl-(1-3)-arabinopyranosylcaulophyllogenin-28-O-rhamnopyranosyl-(1-4)-glucopyranosyl-(1-6)-glucopyranosyl ester
  • 3-O-glucopyranosyl-(1-3)-arabinopyranosylechinocystic acid-28-O-rhamnopyranosyl-(1-4)-glucopyranosyl-(1-6)-glucopyranosyl ester
  • Plant Extracts
  • Saponins