Rotavirus genotype G4P[8] and enteric adenovirus in HIV-positive patients with and without diarrhoea in São Paulo State, Brazil

Trans R Soc Trop Med Hyg. 2010 Feb;104(2):165-7. doi: 10.1016/j.trstmh.2009.07.023. Epub 2009 Sep 2.

Abstract

The present study was carried out in order to identify rotavirus and enteric adenovirus in HIV-positive patients with and without diarrhoea, collected in a pre- and early highly active antiretroviral therapy era. Rotavirus was detected in 2.5% (3/118) and adenovirus in 14.4% (17/118) of the samples from patients without diarrhoea. In the patients with diarrhoea, rotavirus was identified in 1.5% (2/133) and adenovirus in 7.5% (10/133). These findings suggest no increased frequency of virus excretion in HIV-infected patients with diarrhoea. The genotype G4P[8] was characterized in all positive rotavirus samples, and this is the first report of rotavirus molecular characterization in HIV-positive patients in Brazil.

MeSH terms

  • AIDS-Related Opportunistic Infections
  • Adenoviridae / isolation & purification*
  • Adenoviridae Infections / epidemiology*
  • Brazil / epidemiology
  • Diarrhea / virology
  • Feces / virology
  • HIV Infections / complications*
  • Humans
  • Polymerase Chain Reaction / methods
  • Rotavirus / genetics*
  • Rotavirus / isolation & purification
  • Rotavirus Infections / epidemiology*