Introduction: The prevalence of sexual dysfunction is high among women; however, sexual dysfunction secondary to anatomical deformity in women is rare. In addition, primary retroperitoneal leiomyomas are very rare clinical conditions.
Aim: To present a case with sexual dysfunction secondary to anatomical deformity.
Methods: In this article, we report the case of a large retroperitoneal leiomyoma causing sexual dysfunction.
Results: After the surgical removal of the large retroperitoneal mass, previous intercourse difficulties had been resolved.
Conclusions: Retroperitoneal tumors may obstruct the vagina by congesting the pelvic area and may be considered as a possible cause of female sexual dysfunction.