Abstract
Salmonella Pathogenicity Island-7 (SPI-7) is a large, mosaic, genetic island, found in several serovars of Salmonella enterica subsp. enterica associated with systemic disease. As well as encoding genes which may aid its own transmission, it carries genes for potential virulence factors such as Vi antigen, SopE effector and type IVB pili. The stability of SPI-7 is of interest with respect to typhoid fever and related vaccines.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Bacterial Proteins / genetics
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Fimbriae Proteins / genetics
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Genomic Islands*
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Humans
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Polysaccharides, Bacterial / genetics*
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Salmonella typhi / classification
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Salmonella typhi / genetics*
Substances
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Bacterial Proteins
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Polysaccharides, Bacterial
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SopE protein, Salmonella
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capsular polysaccharide, Salmonella
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type IVB pili, Salmonella typhi
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Fimbriae Proteins