Bile acids in asymmetric synthesis and chiral discrimination

Chirality. 2010 May 15;22(5):486-94. doi: 10.1002/chir.20769.

Abstract

An overview on the use of bile acid-based compounds able to catalyze transformations, control the stereochemical course of a given reaction, recognize and bind other molecules, is presented. The recent developments in inclusion discrimination of chiral and achiral guests and enantioselective recognition achieved by bile acid are described with suitable examples.

Publication types

  • Review

MeSH terms

  • Bile Acids and Salts / chemical synthesis*
  • Bile Acids and Salts / chemistry*
  • Catalysis
  • Humans
  • Organic Chemicals / chemistry
  • Solutions
  • Stereoisomerism
  • Substrate Specificity

Substances

  • Bile Acids and Salts
  • Organic Chemicals
  • Solutions