No abstract available
Publication types
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Letter
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Substitution*
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Antineoplastic Agents / pharmacology
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Benzamides
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Drug Resistance, Neoplasm
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Fusion Proteins, bcr-abl / antagonists & inhibitors
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Fusion Proteins, bcr-abl / physiology*
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Humans
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Imatinib Mesylate
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Leukemia, Myelogenous, Chronic, BCR-ABL Positive / drug therapy
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Leukemia, Myelogenous, Chronic, BCR-ABL Positive / enzymology
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Leukemia, Myelogenous, Chronic, BCR-ABL Positive / genetics*
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Leukemia, Myelogenous, Chronic, BCR-ABL Positive / pathology
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Mutation, Missense*
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Neoplasm Proteins / antagonists & inhibitors
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Neoplasm Proteins / physiology*
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Piperazines / therapeutic use
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Point Mutation*
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Protein Kinase Inhibitors / pharmacology
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Protein Structure, Tertiary
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Proto-Oncogene Proteins c-akt / genetics*
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Pyrimidines / therapeutic use
Substances
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Antineoplastic Agents
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Benzamides
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Neoplasm Proteins
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Piperazines
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Protein Kinase Inhibitors
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Pyrimidines
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Imatinib Mesylate
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Fusion Proteins, bcr-abl
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AKT1 protein, human
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Proto-Oncogene Proteins c-akt