Potent and selective inhibition of acid sphingomyelinase by bisphosphonates

Angew Chem Int Ed Engl. 2009;48(41):7560-3. doi: 10.1002/anie.200903288.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Apoptosis
  • Cells, Cultured
  • Diphosphonates / chemical synthesis
  • Diphosphonates / chemistry
  • Diphosphonates / metabolism*
  • Female
  • Humans
  • Isoenzymes / antagonists & inhibitors
  • Isoenzymes / metabolism
  • Molecular Structure
  • Rats
  • Rats, Wistar
  • Sphingomyelin Phosphodiesterase / antagonists & inhibitors*
  • Sphingomyelin Phosphodiesterase / metabolism

Substances

  • Diphosphonates
  • Isoenzymes
  • Sphingomyelin Phosphodiesterase