Abstract
Analysis of methicillin-resistant Staphylococcus aureus (MRSA) characterized as USA300 by pulsed-field gel electrophoresis identified two distinct clones. One was similar to community-associated USA300 MRSA (ST8-IVa, t008, and Panton-Valentine leukocidin positive). The second (ST8-IVa, t024, and PVL negative) had different molecular characteristics and epidemiology, suggesting independent evolution. We recommend spa typing and/or PCR to discriminate between the two clones.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Aged
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Bacterial Typing Techniques*
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Cluster Analysis
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Community-Acquired Infections / epidemiology
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Community-Acquired Infections / microbiology*
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DNA, Bacterial / genetics
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Electrophoresis, Gel, Pulsed-Field*
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Genotype
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Humans
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Methicillin-Resistant Staphylococcus aureus / classification*
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Methicillin-Resistant Staphylococcus aureus / genetics*
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Methicillin-Resistant Staphylococcus aureus / isolation & purification
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Molecular Epidemiology
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Staphylococcal Infections / epidemiology
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Staphylococcal Infections / microbiology*