In 1987, the USSR cosmonauts Y. V. Romanenko (326 days), A. I. Laveikin (approximately 176 days), and A. P. Alexandrov (approximately 160 days) made a space mission on Mir. (A. I. Laveikin showed specific cardiovascular responses to exercise tests and was therefore replaced with A. P. Alexandrov). The most important medical result of this mission was that Yu. V. Romanenko, who remained in orbit for 3 months longer than anyone before, working intensively, did not exhibit any changes that were qualitatively different from those observed in previous long-duration space flights. The health status and work performance of other crewmembers were also good, although each of them showed individual responses. The postflight recovery period went smooth.