Gastrointestinal stromal tumor: computed tomographic features

J Med Assoc Thai. 2009 Sep;92(9):1213-9.

Abstract

Objective: To describe anatomical distribution and CT findings of gastrointestinal stromal tumors in Srinagarind Hospital.

Material and method: The abdominal CT images of 16 patients (12 men, 4 women: mean age 49 +/- 17SD) with pathologically proven GISTs during 1998-2005 were retrospectively reviewed. The tumor sites, sizes, borders, growth patterns, patterns of enhancement, and sign of malignancy were evaluated. The findings of benign and malignant GISTs were compared.

Results: Among sixteen patients, the most common location of GISTs was stomach (56.25%). The others were small bowel (43.75%), and tumor size larger than 5 cm. The present study found that the smooth and mixed smooth and irregular surface lesions are equal in number (50%). The growth was extraluminal in 56.25%. Almost all tumors had inhomogeneous density (n = 15). Intratumoral gas (43.75%), fluid (37.5%), and calcification (50.00%), were present in the tumors. All cases showed inhomogeneous contrast enhancement. The CT signs of malignancy found were invasion of the adjacent organ(s) (62.5%), lymphadenopathy (25%), liver metastasis/nodule (18.75%), ascites (6.25%), perilesional fat plane stranding (93.75%), and pleural effusion (6.25%).

Conclusion: The most common site of GISTs is the stomach. The typical tumors appear as inhomogeneous enhancing inhomogeneous extraluminal mass with either well-defined or irregular border. The CT findings cannot be used as a single tool for differentiating the benign from malignant GISTs.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Cohort Studies
  • Female
  • Gastrointestinal Stromal Tumors / diagnostic imaging*
  • Gastrointestinal Stromal Tumors / pathology*
  • Gastrointestinal Stromal Tumors / surgery
  • Humans
  • Male
  • Middle Aged
  • Retrospective Studies
  • Tomography, X-Ray Computed*
  • Young Adult