MOODS: fast search for position weight matrix matches in DNA sequences

Bioinformatics. 2009 Dec 1;25(23):3181-2. doi: 10.1093/bioinformatics/btp554. Epub 2009 Sep 22.

Abstract

MOODS (MOtif Occurrence Detection Suite) is a software package for matching position weight matrices against DNA sequences. MOODS implements state-of-the-art online matching algorithms, achieving considerably faster scanning speed than with a simple brute-force search. MOODS is written in C++, with bindings for the popular BioPerl and Biopython toolkits. It can easily be adapted for different purposes and integrated into existing workflows. It can also be used as a C++ library.

Availability: The package with documentation and examples of usage is available at http://www.cs.helsinki.fi/group/pssmfind. The source code is also available under the terms of a GNU General Public License (GPL).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Base Sequence
  • Computational Biology / methods*
  • Position-Specific Scoring Matrices
  • Sequence Analysis, DNA / methods*
  • Software*