Optimized time-resolved 3D contrast-enhanced MRA at 3T: appreciating the feasibility of assessing cervical paragangliomas

J Neuroradiol. 2010 May;37(2):104-8. doi: 10.1016/j.neurad.2009.08.004. Epub 2009 Sep 24.

Abstract

Objectives: To describe an optimized 3D time-resolved contrast-enhanced MR angiography (3D TR-CE-MRA) at 3T in diagnosing head and neck paragangliomas and assessing their morphology and relation to neighboring vessels.

Methods: In a prospective study, eight consecutive patients presenting cranial cervical masses suspected to be 10 paragangliomas were examined with 3D TR-CE-MRA at 3T. Two neuroradiologists evaluated the overall image quality, the presence of a paraganglioma, the maximum diameter, as well as the vessel invasion.

Results: In all of the cases, the overall image quality was scored as good. The tumors (n=10) were all visualized and localized. The mean maximum diameter was 32.7mm [range 7-80]. Vessel invasion was assessed as uncertain in one case and improbable in nine cases.

Conclusion: 3D TR-CE-MRA at 3T associated with conventional sequences facilitates a comprehensive investigation of paragangliomas, thus providing the anatomical and functional information.

MeSH terms

  • Adult
  • Aged
  • Arteries / pathology
  • Cerebral Angiography / instrumentation
  • Cerebral Angiography / methods*
  • Feasibility Studies
  • Female
  • Head and Neck Neoplasms / blood supply
  • Head and Neck Neoplasms / diagnosis
  • Head and Neck Neoplasms / pathology*
  • Humans
  • Imaging, Three-Dimensional / instrumentation
  • Imaging, Three-Dimensional / methods*
  • Magnetic Resonance Angiography / instrumentation
  • Magnetic Resonance Angiography / methods*
  • Male
  • Middle Aged
  • Organ Size
  • Paraganglioma / blood supply
  • Paraganglioma / diagnosis
  • Paraganglioma / pathology*
  • Time Factors
  • Veins / pathology