Small invasive ductal adenocarcinoma of the pancreas associated with lymphoplasmacytic sclerosing pancreatitis

Pathol Int. 2009 Oct;59(10):744-7. doi: 10.1111/j.1440-1827.2009.02437.x.

Abstract

An asymptomatic 59-year-old man underwent pancreatoduodenectomy for a pancreatic mass that was discovered during a health check-up. Histopathology indicated typical features of lymphoplasmacytic sclerosing pancreatitis (LPSP) or autoimmune pancreatitis along with the presence of abundant IgG4-positive plasma cells throughout the mass. A small invasive ductal adenocarcinoma was observed in the center of the area affected by LPSP. The present case suggests that LPSP may be closely related to carcinogenesis of the pancreas.

Publication types

  • Case Reports

MeSH terms

  • Autoimmune Diseases / complications
  • Autoimmune Diseases / pathology*
  • Autoimmune Diseases / surgery
  • Carcinoma, Pancreatic Ductal / complications
  • Carcinoma, Pancreatic Ductal / pathology*
  • Carcinoma, Pancreatic Ductal / surgery
  • Cholangiopancreatography, Endoscopic Retrograde
  • Humans
  • Immunoglobulin G / metabolism
  • Incidental Findings
  • Male
  • Middle Aged
  • Pancreas / pathology*
  • Pancreatic Neoplasms / complications
  • Pancreatic Neoplasms / pathology*
  • Pancreatic Neoplasms / surgery
  • Pancreatitis, Chronic / complications
  • Pancreatitis, Chronic / pathology*
  • Pancreatitis, Chronic / surgery
  • Plasma Cells / metabolism
  • Plasma Cells / pathology
  • Sclerosis
  • Treatment Outcome

Substances

  • Immunoglobulin G