Abstract
During fall 2008, an outbreak of hand, foot, and mouth disease (HFMD) with onychomadesis (nail shedding) as a common feature occurred in Finland. We identified an unusual enterovirus type, coxsackievirus A6 (CVA6), as the causative agent. CVA6 infections may be emerging as a new and major cause of epidemic HFMD.
MeSH terms
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Adult
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Child
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Communicable Diseases, Emerging / epidemiology
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Communicable Diseases, Emerging / pathology
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Communicable Diseases, Emerging / virology*
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Coxsackievirus Infections / epidemiology
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Coxsackievirus Infections / pathology
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Coxsackievirus Infections / virology*
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DNA Primers
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Disease Outbreaks*
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Enterovirus* / classification
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Enterovirus* / isolation & purification
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Enterovirus* / pathogenicity
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Female
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Finland / epidemiology
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Hand, Foot and Mouth Disease / epidemiology
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Hand, Foot and Mouth Disease / pathology
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Hand, Foot and Mouth Disease / virology*
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Humans
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Male
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Nails, Malformed / virology
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Phylogeny
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Reverse Transcriptase Polymerase Chain Reaction
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Species Specificity