Abstract
Retinal pigment epithelium (RPE) is a valuable cell type for a number of blinding disorders. In this issue of Cell Stem Cell, Idelson et al. (2009) use Nicotinamide and Activin A to markedly improve RPE yield from human embryonic stem cells.
MeSH terms
-
Activin Receptors, Type I / pharmacology
-
Activin Receptors, Type II / pharmacology
-
Activins / pharmacology
-
Animals
-
Cell Differentiation / drug effects
-
Cell Line
-
Cell Transplantation
-
Embryonic Stem Cells / cytology*
-
Embryonic Stem Cells / drug effects
-
Embryonic Stem Cells / ultrastructure
-
Epithelial Cells / cytology*
-
Epithelial Cells / drug effects
-
Epithelial Cells / ultrastructure
-
Fibroblast Growth Factor 2 / pharmacology
-
Humans
-
Rats
-
Retinal Pigment Epithelium / cytology*
-
Transforming Growth Factor beta / pharmacology
Substances
-
Transforming Growth Factor beta
-
activin A
-
Fibroblast Growth Factor 2
-
Activins
-
Activin Receptors, Type I
-
Activin Receptors, Type II