Methylation of PTEN as a prognostic factor in malignant melanoma of the skin

J Invest Dermatol. 2010 Feb;130(2):620-2. doi: 10.1038/jid.2009.226. Epub 2009 Oct 1.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • DNA Methylation*
  • Disease Progression
  • Disease-Free Survival
  • Epigenesis, Genetic
  • Gene Expression Regulation, Neoplastic
  • Humans
  • Melanoma / diagnosis*
  • Melanoma / genetics*
  • Melanoma / metabolism
  • Mutation
  • PTEN Phosphohydrolase / genetics*
  • Point Mutation
  • Prognosis
  • Promoter Regions, Genetic
  • Proportional Hazards Models
  • Skin Neoplasms / diagnosis*
  • Skin Neoplasms / genetics*
  • Skin Neoplasms / metabolism

Substances

  • PTEN Phosphohydrolase
  • PTEN protein, human