A detailed multipoint gene map of chromosome 1q

K H Buetow; D Nishimura; Y Nakamura; O Jiang; J C Murray

doi:10.1016/0888-7543(90)90220-o

A detailed multipoint gene map of chromosome 1q

Genomics. 1990 Sep;8(1):13-21. doi: 10.1016/0888-7543(90)90220-o.

Authors

K H Buetow¹, D Nishimura, Y Nakamura, O Jiang, J C Murray

Affiliation

¹ Division of Population Science, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111.

PMID: 1981991
DOI: 10.1016/0888-7543(90)90220-o

Abstract

Utilizing genotyping data for 23 markers, we have constructed a 21-locus multipoint genetic map of the long arm of chromosome 1. Five new RFLPs are reported. The map integrates anonymous loci from previous primary linkage maps and incorporates markers for 10 coding sequences. These markers form a continuous linkage group of 85 cM in males and 141 cM in females. The map was constructed employing the LINKAGE and CRIMAP computational methodologies via a stepwise algorithm.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

MeSH terms

Algorithms
Chromosome Mapping
Chromosomes, Human, Pair 1*
DNA Probes
Data Interpretation, Statistical
Humans
Polymorphism, Restriction Fragment Length
Sex Characteristics

Substances

DNA Probes

Grants and funding

etc