[Genetic polymorphism of CYP-450 in drug development]

Nihon Yakurigaku Zasshi. 2009 Oct;134(4):212-5. doi: 10.1254/fpj.134.212.

[Article in Japanese]

Authors

Shinpei Nonen¹, Junichi Azuma

Affiliation

¹ [email protected]

PMID: 19828926
DOI: 10.1254/fpj.134.212

No abstract available

Publication types

Review

MeSH terms

Aryl Hydrocarbon Hydroxylases / genetics*
Aryl Hydrocarbon Hydroxylases / metabolism
Clinical Trials, Phase I as Topic
Cytochrome P-450 CYP2C19
Cytochrome P-450 CYP2C9
Cytochrome P-450 CYP2D6 / genetics*
Cytochrome P-450 CYP2D6 / metabolism
Drug Discovery*
Pharmacogenetics
Pharmacokinetics
Polymorphism, Genetic*
Precision Medicine

Substances

CYP2C9 protein, human
Cytochrome P-450 CYP2C9
Aryl Hydrocarbon Hydroxylases
CYP2C19 protein, human
Cytochrome P-450 CYP2C19
Cytochrome P-450 CYP2D6