Inverted papilloma arising primarily from the lacrimal sac

Orbit. 2009;28(2-3):181-4. doi: 10.1080/01676830802692914.

Abstract

A 24-year-old female was referred with epiphora and a non-tender swelling within the right lacrimal fossa, present for 6 months. There were no previous episodes of dacryocystitis. Computed tomography showed a homogenous mass within the lacrimal fossa without contrast enhancement. Pathology following resection of the whole lacimal sac revealed the presence of an inverted papilloma (IP) with a sharp transition between the papilloma and the normal lacrimal duct epithelium. In situ hybridisation was positive for low risk HPV subtypes. An IP is a benign but infiltrative epithelial neoplasm with malignant potential characterised by a high recurrence rate. Majority of cases arise from the nasal wall and paranasal sinuses. In this case report, we demonstrate an IP confined to the lacrimal sac with clear-cut pathology proof, which implicates the lacrimal sac as a primary site of origin.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Contrast Media
  • Dacryocystorhinostomy / methods*
  • Eye Neoplasms / diagnostic imaging
  • Eye Neoplasms / pathology*
  • Eye Neoplasms / surgery
  • Female
  • Follow-Up Studies
  • Humans
  • Immunohistochemistry
  • Lacrimal Apparatus / diagnostic imaging
  • Lacrimal Apparatus / pathology*
  • Lacrimal Apparatus / surgery
  • Neoplasm Invasiveness / pathology
  • Neoplasm Staging
  • Papilloma, Inverted / diagnostic imaging
  • Papilloma, Inverted / pathology*
  • Papilloma, Inverted / surgery
  • Risk Assessment
  • Tomography, X-Ray Computed / methods
  • Treatment Outcome
  • Young Adult

Substances

  • Contrast Media