Abstract
The dihydrated potassium salt of the complex anion [VO(O(2))NTA](2-) (NTA = nitrilotriacetate anion, [N(CH(2)-COO)(3)](3-)) was thoroughly characterized by electronic and vibrational (infrared and Raman) spectroscopies. The bioactivity of the complex on the cell proliferation was tested on three cell lines in culture (UMR106 rat osteosarcoma-derived cells, Caco-2 derived from a human colon adenocarcinoma, and RAW 264.7, a macrophage murine cell line).
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Antineoplastic Agents / chemical synthesis
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Antineoplastic Agents / chemistry*
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Antineoplastic Agents / pharmacology*
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Caco-2 Cells
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Cell Line
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Cell Line, Tumor
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Cell Proliferation / drug effects
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Crystallography, X-Ray
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Humans
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Molecular Structure
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Rats
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Spectrum Analysis
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Vanadium Compounds / chemical synthesis
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Vanadium Compounds / chemistry*
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Vanadium Compounds / pharmacology*
Substances
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Antineoplastic Agents
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Vanadium Compounds