Treatment of slow-transit constipation with sacral nerve modulation

Colorectal Dis. 2010 Nov;12(11):1149-52. doi: 10.1111/j.1463-1318.2009.02067.x.

Abstract

Aim: Constipation is common and a selection of the best treatment is difficult, especially for slow-transit constipation (STC). The aim of the study was to assess the effect of sacral nerve modulation (SNM) on STC.

Method: A retrospective analysis of patients with STC, treated with SNM was undertaken. All were evaluated by cinedefecography, colon transit-time, Cleveland Clinic Constipation Score (CCS), SF-36 Quality of Life (QoL) and a bowel diary. Initially, all patients underwent a temporary implant for 4 weeks. The criteria of success were disappearance of necessity for laxatives or enema requirement, and improvement in QoL.

Results: Fifteen patients with STC were treated from March 2003 to May 2006. Nine (60%) underwent permanent implantation. After SNM, the mean improvement of Wexner Constipation Score (CCS) and QoL was 10 and 6.2 respectively. There were no complications. The mean follow-up period was 42 months.

Conclusion: Sacral nerve modulation seems to be a useful option for STC.

MeSH terms

  • Adult
  • Chronic Disease
  • Constipation / physiopathology
  • Constipation / therapy*
  • Defecation / physiology*
  • Electric Stimulation Therapy*
  • Electrodes, Implanted
  • Female
  • Gastrointestinal Transit / physiology*
  • Humans
  • Intestine, Large / innervation*
  • Lumbosacral Plexus
  • Male
  • Middle Aged
  • Retrospective Studies
  • Treatment Outcome