22G-RNAs in transposon silencing and centromere function

Mol Cell. 2009 Oct 23;36(2):170-1. doi: 10.1016/j.molcel.2009.10.010.

Abstract

Three recent papers (Gu et al., 2009; Claycomb et al., 2009; van Wolfswinkel et al., 2009) provide evidence that links a new class of small RNAs and Argonaute-associated complexes to centromere function and genome surveillance.

MeSH terms

  • Animals
  • Caenorhabditis elegans / genetics
  • Centromere / metabolism*
  • DNA Transposable Elements / genetics*
  • Gene Silencing*
  • Genome / genetics
  • Models, Genetic
  • RNA, Helminth / metabolism
  • RNA, Small Interfering / metabolism*

Substances

  • DNA Transposable Elements
  • RNA, Helminth
  • RNA, Small Interfering