Escherichia coli as reservoir for macrolide resistance genes

Emerg Infect Dis. 2009 Oct;15(10):1648-50. doi: 10.3201/eid1510.090696.

Abstract

The plasmid-borne mph(A) gene that confers resistance to azithromycin and has recently emerged in Shigella sonnei is present in multidrug- and non-multidrug-resistant Escherichia coli isolates from 4 continents. Further spread of mph(A) to Shigella and Salmonella spp. may be expected.

MeSH terms

  • Drug Resistance, Multiple, Bacterial / genetics*
  • Escherichia coli / drug effects*
  • Escherichia coli / genetics*
  • Escherichia coli Proteins / genetics
  • Escherichia coli Proteins / metabolism
  • Gene Expression Regulation, Bacterial
  • Macrolides / pharmacology*
  • Microbial Sensitivity Tests

Substances

  • Escherichia coli Proteins
  • Macrolides