Implantation of tumor xenografts in nude mice: an improved methodology

J Surg Oncol. 1991 Jan;46(1):40-2. doi: 10.1002/jso.2930460110.

Abstract

Xenografting of neoplasms is a common technique in cancer research. Implantation of non-uniform tumor tissue fragments often yields tumor nodules of irregular size and shape, which is disadvantageous. We therefore developed a device to standardize size and shape of such implants. This instrument is effective, inexpensive to fabricate, and simple to use.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Equipment Design
  • Male
  • Mice
  • Mice, Nude
  • Neoplasm Transplantation / methods*
  • Quality Control
  • Transplantation, Heterologous