Abstract
We describe the challenging case of a patient presenting with extensive, eruptive mid-facial squamous cell carcinomas (SCCs) and keratoacanthomas (KAs) consequent to radiotherapy. Our patient had a personal and family history of multiple KAs and SCCs. Multiple self-healing squamous epithelioma, otherwise known as Ferguson-Smith disease, was diagnosed. This case presented a therapeutic challenge to preserve tissue and avoid severe facial disfigurement. We found oral acitretin to be the treatment of choice.
MeSH terms
-
Acitretin / therapeutic use*
-
Carcinoma, Squamous Cell / drug therapy
-
Carcinoma, Squamous Cell / pathology
-
Carcinoma, Squamous Cell / radiotherapy*
-
Facial Neoplasms / drug therapy
-
Facial Neoplasms / pathology
-
Facial Neoplasms / radiotherapy*
-
Humans
-
Keratoacanthoma / drug therapy
-
Keratoacanthoma / pathology
-
Keratoacanthoma / radiotherapy*
-
Keratolytic Agents / therapeutic use
-
Male
-
Middle Aged
-
Neoplasms, Multiple Primary / drug therapy
-
Neoplasms, Multiple Primary / pathology
-
Neoplasms, Multiple Primary / radiotherapy*
-
Neoplasms, Radiation-Induced / drug therapy
-
Neoplastic Syndromes, Hereditary / drug therapy
-
Neoplastic Syndromes, Hereditary / pathology
-
Neoplastic Syndromes, Hereditary / radiotherapy
-
Skin Neoplasms / drug therapy
-
Skin Neoplasms / pathology
-
Skin Neoplasms / radiotherapy*
Substances
-
Keratolytic Agents
-
Acitretin