(1)H, (15)N, and (13)C chemical shift assignments of mouse HOXA13 DNA binding domain

Biomol NMR Assign. 2009 Dec;3(2):199-201. doi: 10.1007/s12104-009-9174-4. Epub 2009 Jun 24.

Abstract

The homeobox gene (HOXA13) codes for a transcription factor protein that binds to AT-rich DNA sequences and controls expression of many important proteins during embryonic morphogenesis. We report complete NMR chemical shift assignments of the mouse HOXA13 DNA binding domain (A13DBD; BMRB no. 16252).

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • DNA / metabolism*
  • Homeodomain Proteins / chemistry*
  • Homeodomain Proteins / metabolism*
  • Hydrogen-Ion Concentration
  • Mice
  • Nuclear Magnetic Resonance, Biomolecular
  • Protein Structure, Tertiary
  • Substrate Specificity

Substances

  • Homeodomain Proteins
  • homeobox protein HOXA13
  • DNA