Embryogenesis: Degenerate phosphatases control the oocyte-to-embryo transition

Cassandra S Heighington; Edward T Kipreos

doi:10.1016/j.cub.2009.09.032

Embryogenesis: Degenerate phosphatases control the oocyte-to-embryo transition

Curr Biol. 2009 Nov 3;19(20):R939-41. doi: 10.1016/j.cub.2009.09.032.

Authors

Cassandra S Heighington¹, Edward T Kipreos

Affiliation

¹ Departments of Genetics, University of Georgia, Athens, 30602, USA.

PMID: 19889367
DOI: 10.1016/j.cub.2009.09.032

Abstract

The oocyte-to-embryo transition requires drastic reorganizations within a short timeframe. Recent studies show that, in the nematode Caenorhabditis elegans, phosphotyrosine-binding pseudo-phosphatases are key regulators of this critical developmental transition.

Publication types

Comment

MeSH terms

Animals
Binding Sites
Caenorhabditis elegans / cytology
Caenorhabditis elegans / embryology*
Caenorhabditis elegans / enzymology
Caenorhabditis elegans Proteins / chemistry
Caenorhabditis elegans Proteins / metabolism
Caenorhabditis elegans Proteins / physiology*
Embryonic Development / physiology*
Phosphotyrosine / metabolism
Protein Tyrosine Phosphatases / chemistry
Protein Tyrosine Phosphatases / physiology*
Protein-Tyrosine Kinases / metabolism*
Protein-Tyrosine Kinases / physiology

Substances

Caenorhabditis elegans Proteins
EGG-4 protein, C elegans
EGG-5 protein, C elegans
Phosphotyrosine
MBK-2 protein, C elegans
Protein-Tyrosine Kinases
EGG-3 protein, C elegans
Protein Tyrosine Phosphatases