Abstract
The hybrid technique of PET/CT has significantly impacted the imaging and management of HNSCC since its introduction in 2001 and has become the technique of choice for imaging of this cancer. Diagnostic FDG-PET/CT is useful for identification of an unknown primary tumor, delineation of extent of primary tumor, detection of regional lymph node involvement even in a normal-sized node, detection of distant metastases and occasional synchronous primary tumor, assessment of therapy response, and long-term surveillance for recurrence and metastases. The role of PET/CT is evolving in radiation therapy planning. Combined diagnostic PET/CT provides the best anatomic and metabolic in vivo information for the comprehensive management of HNSCC.
MeSH terms
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Biopsy, Fine-Needle
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Carcinoma, Squamous Cell / diagnostic imaging*
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Carcinoma, Squamous Cell / pathology
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Carcinoma, Squamous Cell / secondary
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Carcinoma, Squamous Cell / therapy
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Disease Progression
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Fluorodeoxyglucose F18*
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Follow-Up Studies
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Humans
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Image Processing, Computer-Assisted*
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Lymphatic Metastasis / diagnostic imaging
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Lymphatic Metastasis / pathology
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Neoplasm Recurrence, Local / diagnostic imaging
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Neoplasm Recurrence, Local / pathology
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Neoplasm Recurrence, Local / therapy
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Neoplasm Staging
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Neoplasm, Residual / diagnostic imaging
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Neoplasm, Residual / pathology
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Neoplasm, Residual / therapy
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Neoplasms, Multiple Primary / diagnostic imaging
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Neoplasms, Multiple Primary / pathology
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Neoplasms, Multiple Primary / therapy
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Neoplasms, Unknown Primary / diagnostic imaging
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Otorhinolaryngologic Neoplasms / diagnostic imaging*
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Otorhinolaryngologic Neoplasms / pathology
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Otorhinolaryngologic Neoplasms / secondary
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Otorhinolaryngologic Neoplasms / therapy
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Positron-Emission Tomography*
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Sensitivity and Specificity
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Tomography, X-Ray Computed*
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Tumor Burden
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Ultrasonography