Identification of the Geobacter metallireducens bamVW two-component system, involved in transcriptional regulation of aromatic degradation

Appl Environ Microbiol. 2010 Jan;76(1):383-5. doi: 10.1128/AEM.02255-09. Epub 2009 Nov 13.

Abstract

Regulation of aromatic degradation in obligate anaerobes was studied in the Fe(III)-respiring model organism Geobacter metallireducens GS-15. A two-component system and a sigma54-dependent promoter were identified that are both involved in the regulation of the gene coding for benzoate-coenzyme A ligase, catalyzing the initial step of benzoate degradation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adaptation, Physiological
  • Artificial Gene Fusion
  • Bacterial Proteins / biosynthesis
  • Base Sequence
  • Binding Sites
  • Coenzyme A Ligases / biosynthesis
  • Gene Expression Regulation, Bacterial*
  • Genes, Reporter
  • Geobacter / genetics
  • Geobacter / metabolism*
  • Hydrocarbons, Aromatic / metabolism*
  • Molecular Sequence Data
  • Promoter Regions, Genetic
  • RNA Polymerase Sigma 54 / metabolism
  • Signal Transduction*
  • Transcription Initiation Site
  • beta-Galactosidase / biosynthesis
  • beta-Galactosidase / genetics

Substances

  • Bacterial Proteins
  • Hydrocarbons, Aromatic
  • RNA Polymerase Sigma 54
  • beta-Galactosidase
  • Coenzyme A Ligases
  • benzoate coenzyme A ligase