Abstract
Regulation of aromatic degradation in obligate anaerobes was studied in the Fe(III)-respiring model organism Geobacter metallireducens GS-15. A two-component system and a sigma54-dependent promoter were identified that are both involved in the regulation of the gene coding for benzoate-coenzyme A ligase, catalyzing the initial step of benzoate degradation.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adaptation, Physiological
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Artificial Gene Fusion
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Bacterial Proteins / biosynthesis
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Base Sequence
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Binding Sites
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Coenzyme A Ligases / biosynthesis
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Gene Expression Regulation, Bacterial*
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Genes, Reporter
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Geobacter / genetics
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Geobacter / metabolism*
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Hydrocarbons, Aromatic / metabolism*
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Molecular Sequence Data
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Promoter Regions, Genetic
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RNA Polymerase Sigma 54 / metabolism
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Signal Transduction*
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Transcription Initiation Site
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beta-Galactosidase / biosynthesis
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beta-Galactosidase / genetics
Substances
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Bacterial Proteins
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Hydrocarbons, Aromatic
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RNA Polymerase Sigma 54
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beta-Galactosidase
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Coenzyme A Ligases
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benzoate coenzyme A ligase