Practitioners of community-based participatory research (CBPR) must overcome numerous barriers in order to include research participants as equal partners in decision-making. The decision-making processes of stakeholders (including research participants) of one international CBPR project based in the middle belt of Ghana were analyzed through qualitative focus group and interview data, as well as direct observation of formal meetings. Using modified grounded theory to interpret our data, we find that despite the intentions of extracommunity stakeholders, ordinary community members do not experience full ownership of the governance of the research enterprise. We conclude that organizational philosophy, cultural expectations, and environmental context can help to explain differential perceptions of stakeholders and function as barriers to full partnership.