Abstract
Five new C(21) steroidal glycosides (1-5) were isolated from the stems of Marsdenia tenacissima. The chemical structures and relative configurations of the new compounds were elucidated by mass spectrometry and NMR spectroscopy. Cellular assay of these compounds showed that they are weak cytotoxic to various cell lines.
Copyright 2009 Elsevier Inc. All rights reserved.
MeSH terms
-
Antineoplastic Agents / chemistry
-
Antineoplastic Agents / isolation & purification*
-
Antineoplastic Agents / pharmacology*
-
Cell Survival / drug effects
-
Glycosides / chemistry
-
Glycosides / isolation & purification*
-
Humans
-
Marsdenia / chemistry*
-
Plant Stems / chemistry*
-
Steroids / chemistry
-
Steroids / isolation & purification*
Substances
-
Antineoplastic Agents
-
Glycosides
-
Steroids