Efficacy of double-arterial phase gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid-enhanced liver magnetic resonance imaging compared with double-arterial phase multi-detector row helical computed tomography

J Comput Assist Tomogr. 2009 Nov-Dec;33(6):887-92. doi: 10.1097/RCT.0b013e3181a1ca7e.

Abstract

Objective: To evaluate the efficacy of double-arterial phase gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging (MRI) using 3-dimensional gradient-echo sequences compared with double-arterial phase multi-detector row helical computed tomography (CT).

Methods: This study included 15 patients with 24 surgically proven hepatocellular carcinomas. Dynamic MRI and CT were evaluated by 2 observers using a 4-point scale. We compared the scores of double-arterial phase MRI and CT for each observer and determined whether a significant difference existed.

Results: Using MRI, 83% and 79% of the lesions were considered hypervascular by the two observers versus 88% for both observers using CT. The difference between MRI and CT was not significant.

Conclusions: Double-arterial phase gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid-enhanced MRI is as useful as double-arterial phase multi-detector row helical CT for detecting the hypervascularity of hepatocellular carcinoma.

MeSH terms

  • Aged
  • Carcinoma, Hepatocellular / blood supply
  • Carcinoma, Hepatocellular / diagnosis*
  • Carcinoma, Hepatocellular / diagnostic imaging
  • Carcinoma, Hepatocellular / pathology
  • Contrast Media
  • Female
  • Gadolinium DTPA*
  • Humans
  • Liver Neoplasms / blood supply
  • Liver Neoplasms / diagnosis*
  • Liver Neoplasms / diagnostic imaging
  • Liver Neoplasms / pathology
  • Magnetic Resonance Imaging / methods*
  • Male
  • Middle Aged
  • Statistics, Nonparametric
  • Tomography, Spiral Computed / methods*

Substances

  • Contrast Media
  • gadolinium ethoxybenzyl DTPA
  • Gadolinium DTPA