Membrane proteomes of Pseudomonas aeruginosa and Acinetobacter baumannii

E Dé; P Cosette; L Coquet; A Siroy; S Alexandre; A Duncan; B Naudin; C Rihouey; A Schaumann; G A Junter; T Jouenne

doi:10.1016/j.patbio.2009.10.005

Membrane proteomes of Pseudomonas aeruginosa and Acinetobacter baumannii

Pathol Biol (Paris). 2011 Dec;59(6):e136-9. doi: 10.1016/j.patbio.2009.10.005. Epub 2009 Nov 25.

Authors

E Dé¹, P Cosette, L Coquet, A Siroy, S Alexandre, A Duncan, B Naudin, C Rihouey, A Schaumann, G A Junter, T Jouenne

Affiliation

¹ CNRS FRE 3101, Équipe BRICs, Laboratoire Polymères, Biopolymères, Surfaces, Université de Rouen, 76821 Mont-Saint-Aignan, France.

PMID: 19942379
DOI: 10.1016/j.patbio.2009.10.005

Abstract

Acinetobacter baumannii and Pseudomonas aeruginosa are known for their intrinsic resistance to antibiotics. Between mechanisms involved in this resistance, diminished expression of outer membrane proteins and up-regulation of efflux pumps play an important role. The characterization of membrane proteins is consequently necessary because of their importance in the antibiotic resistance but also in virulence. This review presents proteomic investigations aiming to describe the protein content of the membranes of these two bacterial species.

Publication types

Review

MeSH terms

Acinetobacter Infections / metabolism
Acinetobacter baumannii / metabolism*
Bacterial Proteins / analysis*
Bacterial Proteins / metabolism
Humans
Membrane Proteins / analysis*
Membrane Proteins / metabolism
Proteome / analysis*
Proteomics
Pseudomonas Infections / microbiology
Pseudomonas aeruginosa / metabolism*

Substances

Bacterial Proteins
Membrane Proteins
Proteome