Protein kinase C-alpha negatively regulates EGF-induced PLC-epsilon activity through direct phosphorylation

Adv Enzyme Regul. 2010;50(1):178-89. doi: 10.1016/j.advenzreg.2009.10.023. Epub 2009 Dec 3.

Authors

Sanguk Yun¹, Ha-Young Byun, Young-Seok Oh, Yong Ryoul Yang, Sung Ho Ryu, Pann-Ghill Suh

Affiliation

¹ Department of Life Science and Division of Molecular and Life Sciences, Pohang University of Science and Technology, Pohang 790-784, Republic of Korea.

PMID: 19948183
DOI: 10.1016/j.advenzreg.2009.10.023

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
COS Cells
Cell Membrane / metabolism
Chlorocebus aethiops
Enzyme Activation
Epidermal Growth Factor / metabolism*
Isoenzymes / genetics
Isoenzymes / metabolism*
Phosphoinositide Phospholipase C / metabolism*
Phosphorylation
Protein Kinase C-alpha / metabolism*
Recombinant Fusion Proteins / genetics
Recombinant Fusion Proteins / metabolism
Signal Transduction / physiology

Substances

Isoenzymes
Recombinant Fusion Proteins
Epidermal Growth Factor
Protein Kinase C-alpha
Phosphoinositide Phospholipase C
phospholipase C epsilon