Abstract
A wide range of methodology will be needed to bridge the gap between genome sequence and mechanistic understanding in biology. Recent advances in high-throughput genetic screening address this task.
MeSH terms
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Bacteria
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Epistasis, Genetic
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Gene Deletion
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Genes / genetics
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Genes / physiology*
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Genome / genetics*
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Genome / physiology
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High-Throughput Screening Assays / methods*
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Microscopy / methods
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Mutation
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Phenotype*
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Saccharomyces cerevisiae / genetics
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Sequence Analysis, DNA / methods*
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Sequence Analysis, DNA / trends