Outbreak of antiviral drug-resistant influenza a in long-term care facility, Illinois, USA, 2008

Nila J Dharan; Monica Patton; Alicia M Siston; Julie Morita; Enrique Ramirez; Teresa R Wallis; Varough Deyde; Larisa V Gubareva; Alexande I Klimov; Joseph S Bresee; Alicia M Fry

doi:10.3201/eid1512.081644

Outbreak of antiviral drug-resistant influenza a in long-term care facility, Illinois, USA, 2008

Emerg Infect Dis. 2009 Dec;15(12):1973-6. doi: 10.3201/eid1512.081644.

Authors

Nila J Dharan¹, Monica Patton, Alicia M Siston, Julie Morita, Enrique Ramirez, Teresa R Wallis, Varough Deyde, Larisa V Gubareva, Alexande I Klimov, Joseph S Bresee, Alicia M Fry

Affiliation

¹ Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.

Abstract

An outbreak of oseltamivir-resistant influenza A (H1N1) occurred in a long-term care facility. Eight (47%) of 17 and 1 (6%) of 16 residents in 2 wards had oseltamivir-resistant influenza A virus (H1N1) infections. Initial outbreak response included treatment and prophylaxis with oseltamivir. The outbreak abated, likely because of infection control measures.

MeSH terms

Adolescent
Adult
Antiviral Agents / pharmacology*
Disease Outbreaks*
Drug Resistance, Viral
Humans
Illinois / epidemiology
Influenza A Virus, H1N1 Subtype / drug effects*
Influenza, Human / drug therapy
Influenza, Human / epidemiology*
Long-Term Care
Middle Aged
Oseltamivir / pharmacology*
Time Factors

Substances

Antiviral Agents
Oseltamivir