Light-controlled retinal stimulation on rabbit using CMOS-based flexible multi-chip stimulator

T Tokuda; Y Takeuchi; T Noda; K Sasagawa; K Nishida; Y Kitaguchi; T Fujikado; Y Tano; J Ohta

doi:10.1109/IEMBS.2009.5333809

Light-controlled retinal stimulation on rabbit using CMOS-based flexible multi-chip stimulator

Annu Int Conf IEEE Eng Med Biol Soc. 2009:2009:646-9. doi: 10.1109/IEMBS.2009.5333809.

Authors

T Tokuda¹, Y Takeuchi, T Noda, K Sasagawa, K Nishida, Y Kitaguchi, T Fujikado, Y Tano, J Ohta

Affiliation

¹ Nara Institute Science and Technology, Takayama-cho 8916-5, Ikoma, Nara, 630-0192, Japan. [email protected]

PMID: 19964235
DOI: 10.1109/IEMBS.2009.5333809

Abstract

We implemented a light-sensing function on CMOS-based multi-chip stimulator for retinal prosthesis. Using the light-sensing circuitry attached to each stimulation electrode, the flexible multi-chip stimulator is capable of image-based patterned stimulation. We verified the function of the light-controlled decision based on the light intensity measured just beside the stimulation site. We also experimentally demonstrated in vivo retinal stimulation on rabbit's retina with light-controlled decision. The result of the present work is a simplified demonstration for the concept of retinal prosthesis with on-site imaging.

Publication types

Evaluation Study
Research Support, Non-U.S. Gov't

MeSH terms

Electric Stimulation Therapy / instrumentation*
Electrodes, Implanted*
Equipment Design
Equipment Failure Analysis
Image Interpretation, Computer-Assisted / instrumentation*
Light
Photic Stimulation / instrumentation*
Prostheses and Implants*
Retina / physiology*
Semiconductors
Signal Processing, Computer-Assisted / instrumentation*