Engineering dendritic aptamer assemblies as superior inhibitors of protein function

Chem Asian J. 2010 Jan 4;5(1):56-9. doi: 10.1002/asia.200900421.

Authors

Youngmi Kim¹, Donn M Dennis, Tim Morey, Liu Yang, Weihong Tan

Affiliation

¹ Department of Chemistry, Center for Research at the Bio/Nano Interface, Shands Cancer Center, Genetics Institute, University of Florida, Gainesville, FL, Gainesville, FL 32611-7200, USA.

PMID: 19967736
DOI: 10.1002/asia.200900421

No abstract available

Publication types

Research Support, N.I.H., Extramural
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Aptamers, Nucleotide / chemistry*
Aptamers, Nucleotide / pharmacology
Base Sequence
DNA Probes / chemistry
Genetic Engineering
Humans
Prothrombin Time
Serine Proteinase Inhibitors / chemistry*
Serine Proteinase Inhibitors / pharmacology
Thrombin / antagonists & inhibitors
Thrombin / metabolism*

Substances

Aptamers, Nucleotide
DNA Probes
Serine Proteinase Inhibitors
Thrombin