Effect of genistein therapy on plasma levels of asymmetric dimethylarginine in healthy postmenopausal women: a randomized, placebo-controlled study

Fertil Steril. 2010 Jul;94(2):764-6. doi: 10.1016/j.fertnstert.2009.09.057. Epub 2009 Dec 11.

Abstract

The aim of this study was to investigate the effects of pure genistein therapy on asymmetric dimethylarginine in healthy postmenopausal women. Healthy postmenopausal women received pure genistein (n=21) or placebo (n=17) for 6 months, and no statistically significant effects on plasma asymmetric dimethylarginine levels were found with pure genistein treatment.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Arginine / analogs & derivatives*
  • Arginine / blood
  • Atherosclerosis / blood
  • Atherosclerosis / epidemiology
  • Female
  • Genistein / administration & dosage*
  • Humans
  • Middle Aged
  • Phytoestrogens / administration & dosage*
  • Placebos
  • Postmenopause / blood
  • Postmenopause / drug effects*
  • Reference Values
  • Risk Factors

Substances

  • Phytoestrogens
  • Placebos
  • N,N-dimethylarginine
  • Arginine
  • Genistein