Perspectives on protein crystallisation

Takashi Ochi; Victor M Bolanos-Garcia; Vivian Stojanoff; Abel Moreno

doi:10.1016/j.pbiomolbio.2009.12.001

Perspectives on protein crystallisation

Prog Biophys Mol Biol. 2009 Nov;101(1-3):56-63. doi: 10.1016/j.pbiomolbio.2009.12.001. Epub 2009 Dec 11.

Authors

Takashi Ochi¹, Victor M Bolanos-Garcia, Vivian Stojanoff, Abel Moreno

Affiliation

¹ Department of Biochemistry, University of Cambridge, 80 Tennis Court Road CB2 1GA Cambridge, UK.

PMID: 20005246
DOI: 10.1016/j.pbiomolbio.2009.12.001

Abstract

This final part on 'perspectives' is focused on new strategies that can be used to crystallise proteins and improve the crystal quality of macromolecular complexes using any of the methods reviewed in this focused issue. Some advantages and disadvantages, limitations, and plausible applications to high-resolution X-ray crystallography are discussed.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Crystallization / methods*
Crystallography, X-Ray / methods
Models, Chemical
Proteins / chemistry*

Substances

Proteins