Abstract
To improve upon adherence assessment in children with HIV, multimethod adherence strategies (pill count, missed doses, off-schedule dosing) were conducted concurrent with viral load and CD4% biomarker assays. Off-schedule dosing predicted both health status markers, while the more common strategies did not. Findings support inclusion of off-schedule dosing concurrent with collection of biomarkers to assess adherence in children with HIV.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Anti-HIV Agents / administration & dosage*
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CD4 Lymphocyte Count
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Caregivers
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Child
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Cross-Sectional Studies
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Drug Administration Schedule
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Female
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HIV Infections / drug therapy*
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HIV Infections / immunology
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HIV Infections / transmission
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HIV Infections / virology
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Humans
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Infectious Disease Transmission, Vertical
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Interviews as Topic
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Male
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Medication Adherence*
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Patient Compliance / statistics & numerical data*
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Predictive Value of Tests
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Treatment Outcome
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Viral Load / physiology*