Expression of S100B and S100A6 genes during long-term posttetanic potentiation in the hippocampus

O O Sokolova; M B Shtark; P D Lisachev; V O Pustylnyak; I R Pan; O I Epstein

doi:10.1007/s10517-009-0660-6

Expression of S100B and S100A6 genes during long-term posttetanic potentiation in the hippocampus

Bull Exp Biol Med. 2009 Aug;148(2):227-9. doi: 10.1007/s10517-009-0660-6.

Authors

O O Sokolova¹, M B Shtark, P D Lisachev, V O Pustylnyak, I R Pan, O I Epstein

Affiliation

¹ Institute of Molecular Biology and Biophysics, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia.

PMID: 20027335
DOI: 10.1007/s10517-009-0660-6

Abstract

The expression of S100B and S100A6 mRNA in CA1 region of rat hippocampal sections was studied after tetanizing stimulation. The level of S100B expression increased 2-4-fold in comparison with the control after 30 min and gradually returned to the basal level 120 min after tetanization. The level of S100A6 mRNA was very low and did not change after tetanization.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Cell Cycle Proteins / genetics*
Gene Expression Regulation*
Hippocampus / metabolism*
Long-Term Potentiation / genetics*
Male
Nerve Growth Factors / genetics*
Polymerase Chain Reaction
Rats
Rats, Wistar
S100 Calcium Binding Protein A6
S100 Calcium Binding Protein beta Subunit
S100 Proteins / genetics*

Substances

Cell Cycle Proteins
Nerve Growth Factors
S100 Calcium Binding Protein A6
S100 Calcium Binding Protein beta Subunit
S100 Proteins
S100a6 protein, rat
S100b protein, rat