Results of the Abbott RealTime HIV-1 assay for specimens yielding "target not detected" results by the Cobas AmpliPrep/Cobas TaqMan HIV-1 Test

N Esther Babady; Jeffrey J Germer; Joseph D C Yao

doi:10.1128/JCM.01394-09

Results of the Abbott RealTime HIV-1 assay for specimens yielding "target not detected" results by the Cobas AmpliPrep/Cobas TaqMan HIV-1 Test

J Clin Microbiol. 2010 Mar;48(3):969-71. doi: 10.1128/JCM.01394-09. Epub 2009 Dec 30.

Authors

N Esther Babady¹, Jeffrey J Germer, Joseph D C Yao

Affiliation

¹ Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905-0002, USA.

Abstract

No significantly discordant results were observed between the Abbott RealTime HIV-1 assay and the COBAS AmpliPrep/COBAS TaqMan HIV-1 Test (CTM) among 1,190 unique clinical plasma specimens obtained from laboratories located in 40 states representing all nine U.S. geographic regions and previously yielding "target not detected" results by CTM.

Publication types

Comparative Study
Evaluation Study
Multicenter Study

MeSH terms

HIV Infections / diagnosis*
HIV Infections / virology
HIV-1 / genetics
HIV-1 / isolation & purification*
Humans
Molecular Diagnostic Techniques / methods*
Sensitivity and Specificity