Abstract
Novel human adenoviruses (HAdVs) arise from genome recombination. Analysis of HAdV type 55 from an outbreak in China shows a hexon recombination between HAdV-B11 and HAdV-B14, resulting in a genome that is 97.4% HAdV-B14. Sporadic appearances as a re-emergent pathogen and misidentification as "HAdV-B11a" are due to this partial hexon.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Adenovirus Infections, Human / epidemiology*
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Adenovirus Infections, Human / virology
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Adenoviruses, Human / genetics*
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Adenoviruses, Human / isolation & purification*
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Capsid Proteins / genetics
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China / epidemiology
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Communicable Diseases, Emerging / epidemiology*
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Communicable Diseases, Emerging / virology
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Computational Biology
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DNA, Viral / genetics
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Disease Outbreaks*
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Evolution, Molecular
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Humans
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Recombination, Genetic
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Respiratory Tract Infections / epidemiology*
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Respiratory Tract Infections / virology
Substances
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Capsid Proteins
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DNA, Viral
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hexon capsid protein, Adenovirus