Localized perineal cutaneous nodules: a case of recurrent systemic anaplastic large-cell lymphoma

C Hernandez; S N Puangsuvan; A Peterson; J K Robinson

doi:10.1111/j.1365-2230.2009.03448.x

Localized perineal cutaneous nodules: a case of recurrent systemic anaplastic large-cell lymphoma

Clin Exp Dermatol. 2009 Dec;34(8):e722-5. doi: 10.1111/j.1365-2230.2009.03448.x.

Authors

C Hernandez¹, S N Puangsuvan, A Peterson, J K Robinson

Affiliation

¹ Department of Dermatology, University of Illinois at Chicago, Chicago, IL, USA.

PMID: 20055841
DOI: 10.1111/j.1365-2230.2009.03448.x

Abstract

We report an unusual case of localized cutaneous nodules heralding the recurrence of systemic CD30+ anaplastic large-cell lymphoma (ALCL). A 47-year-old woman developed numerous violaceous nodules in the perineal and upper thigh area 3 years after multimodal treatment and complete remission of primary anaplastic large-cell CD30+ lymphoma. Using immunohistochemical and T-cell gene rearrangement analysis, a recurrence of her anaplastic large-cell lymphoma was diagnosed.

Publication types

Case Reports

MeSH terms

Cell Transformation, Neoplastic / genetics
Female
Gene Rearrangement, T-Lymphocyte / genetics
Humans
Ki-1 Antigen / genetics
Lymphoma, Large-Cell, Anaplastic / drug therapy
Lymphoma, Large-Cell, Anaplastic / genetics
Lymphoma, Large-Cell, Anaplastic / pathology*
Middle Aged
Neoplasm Recurrence, Local / genetics
Neoplasm Recurrence, Local / pathology*
Skin Neoplasms / drug therapy
Skin Neoplasms / genetics
Skin Neoplasms / pathology*
Stem Cell Transplantation
Treatment Outcome

Substances

Ki-1 Antigen