The authors describe two proved and two presumed cases of cuboid fractures in toddlers. These children were seen because of their inability to bear weight on the affected foot following a fall. Initial radiographs were normal; however, early scintigraphy revealed focal uptake in the cuboid. Follow-up radiographs demonstrated characteristic sclerosis of the base of the cuboid. Cuboid fractures are another example of a toddler's injury that may be difficult to diagnose at initial physical and radiographic examination.