Construction of a library of rhodol fluorophores for developing new fluorescent probes

Org Lett. 2010 Feb 5;12(3):496-9. doi: 10.1021/ol902706b.

Abstract

A highly efficient and concise synthetic scheme for rhodol fluorophores is developed with palladium-catalyzed amination reaction as the key step. This new synthetic route is utilized to construct a rhodol library, potentially useful for the design of novel fluorescent probes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amination
  • Catalysis
  • Combinatorial Chemistry Techniques*
  • Fluorescent Dyes / chemical synthesis*
  • Fluorescent Dyes / chemistry
  • Heterocyclic Compounds, 4 or More Rings / chemical synthesis*
  • Heterocyclic Compounds, 4 or More Rings / chemistry
  • Molecular Structure
  • Palladium / chemistry*

Substances

  • Fluorescent Dyes
  • Heterocyclic Compounds, 4 or More Rings
  • Palladium